An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells

Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we reasoned that liver NPCs would support the ma...

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Bibliographic Details
Main Authors: Yuta Koui, Taketomo Kido, Toshimasa Ito, Hiroki Oyama, Shin-Wei Chen, Yuki Katou, Katsuhiko Shirahige, Atsushi Miyajima
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117302734