Unique interplay between sugar and lipid in determining the antigenic potency of bacterial antigens for NKT cells.
Invariant natural killer T (iNKT) cells are an evolutionary conserved T cell population characterized by features of both the innate and adaptive immune response. Studies have shown that iNKT cells are required for protective responses to Gram-positive pathogens such as Streptococcus pneumoniae, and...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-11-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC3206013?pdf=render |