Variations in <i>HIF-1α</i> Contributed to High Altitude Hypoxia Adaptation via Affected Oxygen Metabolism in Tibetan Sheep

Variations in <i>HIF-1α</i> Contributed to High Altitude Hypoxia Adaptation via Affected Oxygen Metabolism in Tibetan Sheep

The Tibetan sheep is an indigenous species of the Tibetan plateau and has been well adapted to high-altitude hypoxia. In comparison to lowland sheep breeds, the blood gas indicators have changed and the HIFs signaling pathway is activated in Tibetan sheep. These phenotypic and genetic alterations in...

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Bibliographic Details
Main Authors: Pengfei Zhao, Zhaohua He, Qiming Xi, Hongxian Sun, Yuzhu Luo, Jiqing Wang, Xiu Liu, Zhidong Zhao, Shaobin Li
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Animals
Subjects:
Tibetan sheep
blood gas indicators
<i>HIF-1α</i>
high-altitude hypoxia
adaptation
Online Access:https://www.mdpi.com/2076-2615/12/1/58

Internet

https://www.mdpi.com/2076-2615/12/1/58

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