Circ-NFKB1 sponges miR-203a-5p to regulate ERBB4 expression and promotes IL-1β induced chondrocytes apoptosis

Abstract Background Osteoarthritis (OA) is a chronic disease of the bones and joints that commonly affects middle-aged and elderly individuals, characterized by the degeneration of articular cartilage and inflammation of the joints. The molecular mechanisms of OA urgently need to be further examined...

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Autori principali: Zhao Wang, Hongwei Bao, Jingzhao Hou, Bin Ju, Yong Ji
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2023-07-01
Serie:Journal of Orthopaedic Surgery and Research
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Accesso online:https://doi.org/10.1186/s13018-023-03990-4