UV-induced local immunosuppression in the tumour microenvironment of eccrine porocarcinoma and poroma

Abstract Eccrine porocarcinoma (EPC) is a rare malignant adnexal tumour of the skin. Part of EPCs develop from their benign counterpart, poroma (EP), with chronic light exposure and immunosuppression hypothesized to play a role in the malignant transformation. However, the impact of chronic light ex...

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Bibliographic Details
Main Authors: Maya Puttonen, Jorma Isola, Onni Ylinen, Tom Böhling, Virve Koljonen, Harri Sihto
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09490-5