The enigma of DNA methylation in the mammalian oocyte [version 1; peer review: 4 approved]

The mammalian genome experiences profound setting and resetting of epigenetic patterns during the life-course. This is understood best for DNA methylation: the specification of germ cells, gametogenesis, and early embryo development are characterised by phases of widespread erasure and rewriting of...

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Bibliographic Details
Main Authors: Hannah Demond, Gavin Kelsey
Format: Article
Language:English
Published: F1000 Research Ltd 2020-02-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-146/v1