HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques.

BACKGROUND:Personalized targeted treatment in metastatic breast cancer relies on accurate assessment of molecular aberrations, e.g. overexpression of Human Epidermal growth factor Receptor 2 (HER-2). Molecular interrogation of circulating tumor cells (CTCs) can provide an attractive alternative for...

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Bibliographic Details
Main Authors: Anja Brouwer, Bram De Laere, Pieter-Jan van Dam, Dieter Peeters, Jasper Van Haver, Ellen Sluydts, Ali El Moussaoui, Pauline Mendelaar, Jaco Kraan, Marc Peeters, Steven Van Laere, Luc Dirix
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220906