Chronic myeloid leukemia: past, present, future

The discovery of the Philadelphia chromosome in 1960, and of the BCR-ABL oncogene in 1984, enabled the development in subsequent years of a targeted therapy that revolutionized the treatment of chronic myeloid leukemia, thus changing its natural history. The use of imatinib resulted in a significant...

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Bibliographic Details
Main Authors: Patricia Weinschenker Bollmann, Auro del Giglio
Format: Article
Language:English
Published: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2011-06-01
Series:Einstein (São Paulo)
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082011000200236&tlng=pt