The involvement of E3 ubiquitin ligases in the development and progression of colorectal cancer

Abstract To date, colorectal cancer (CRC) still has limited therapeutic efficacy and poor prognosis and there is an urgent need for novel targets to improve the outcome of CRC patients. The highly conserved ubiquitination modification mediated by E3 ubiquitin ligases is an important mechanism to reg...

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Bibliographic Details
Main Authors: Jie Chen, Haimei Feng, Yiting Wang, Xiaoming Bai, Siqi Sheng, Huiyu Li, Mengxi Huang, Xiaoyuan Chu, Zengjie Lei
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01760-z