STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness

STXBP6, reciprocally regulated with autophagy, reduces triple negative breast cancer aggressiveness

Abstract Background Although autophagy plays a dual role in suppressing or promoting certain cancers, the nature of its involvement in breast cancers remains unclear. Here, we investigated the function of STXBP6, a protein regulating the autophagy‐associated SNARE complex, in triple negative breast...

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Bibliographic Details
Main Authors: Govinda Lenka, Jingxuan Shan, Najeeb Halabi, Sirin W J Abuaqel, Neha Goswami, Frank Schmidt, Shaza Zaghlool, Atilio Reyes Romero, Murugan Subramanian, Salha Boujassoum, Issam Al‐Bozom, Salah Gehani, Noor Al Khori, Davide Bedognetti, Karsten Suhre, Xiaojing Ma, Alexander Dömling, Arash Rafii, Lotfi Chouchane
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Clinical and Translational Medicine
Subjects:
autophagy
metastasis
STXBP6
triple negative breast cancer
tumor suppressor gene
Online Access:https://doi.org/10.1002/ctm2.147

Internet

https://doi.org/10.1002/ctm2.147

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