The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation

The extracellular matrix of lymph node reticular fibers modulates follicle border interactions and germinal center formation

Summary: Germinal center (GC) formation and antibody production in lymph node follicles require coordinated interactions between B-cells, T-cells and dendritic cells (DCs), orchestrated by the extracellular matrix-rich reticular fiber (RF) network. We describe a unique laminin 523-containing RF netw...

Full description

Bibliographic Details
Main Authors: Jian Song, Tushar Deshpande, Xueli Zhang, Melanie-Jane Hannocks, Nils Lycke, Susanna L. Cardell, Lydia Sorokin
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Biological sciences
Immunology
Immune system
Immune response
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008301

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223008301

Similar Items