An efficient feeder-free and chemically-defined expansion strategy for highly purified natural killer cells derived from human cord blood

An efficient feeder-free and chemically-defined expansion strategy for highly purified natural killer cells derived from human cord blood

Introduction: Natural killer cells (NKCs) are immune cells that can attack cancer cells through the direct recognition of ligands without prior sensitization. Cord blood-derived NKCs (CBNKCs) represent a promising tool for allogenic NKC-based cancer immunotherapy. Efficient NKC expansion and decreas...

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Bibliographic Details
Main Authors: Tsutomu Nakazawa, Ryosuke Maeoka, Takayuki Morimoto, Ryosuke Matsuda, Mitsutoshi Nakamura, Fumihiko Nishimura, Shuichi Yamada, Ichiro Nakagawa, Young-Soo Park, Toshihiro Ito, Hiroyuki Nakase, Takahiro Tsujimura
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Regenerative Therapy
Subjects:
Cord blood
Allogeneic NKC
Cell-based immunotherapy
Cancer immunotherapy
Glioblastoma
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320423000445

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http://www.sciencedirect.com/science/article/pii/S2352320423000445

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