Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective

Synthesis of [18F]FMISO, a hypoxia-specific imaging probe for PET, an overview from a radiochemist’s perspective

Abstract Background [18F]fluoromisonidazole ([18F]FMISO, 1H-1-(3-[18F]fluoro-2-hydroxypropyl)-2-nitroimidazole) is a commonly used radiotracer for imaging hypoxic conditions in cells. Since hypoxia is prevalent in solid tumors, [18F]FMISO is in clinical application for decades to explore oxygen dema...

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Bibliografski detalji
Glavni autori: Torsten Kniess, Jörg Zessin, Peter Mäding, Manuela Kuchar, Oliver Kiss, Klaus Kopka
Format: Članak
Jezik:English
Izdano: SpringerOpen 2023-03-01
Serija:EJNMMI Radiopharmacy and Chemistry
Teme:
[18F]FMISO
[18F]fluoromisonidazole
Automated radiosynthesis
FASTlab
Online pristup:https://doi.org/10.1186/s41181-023-00190-7

Internet

https://doi.org/10.1186/s41181-023-00190-7

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