3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways

3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways

Abstract Dietary compounds in cancer prevention have gained significant consideration as a viable method. Indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) are heterocyclic and bioactive chemicals found in cruciferous vegetables like broccoli, cauliflower, cabbage, and brussels sprouts. They a...

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Main Authors: Octavio Daniel Reyes-Hernández, Gabriela Figueroa-González, Laura Itzel Quintas-Granados, Stephany Celeste Gutiérrez-Ruíz, Hector Hernández-Parra, Alejandra Romero-Montero, María Luisa Del Prado-Audelo, Sergio Alberto Bernal-Chavez, Hernán Cortés, Sheila I. Peña-Corona, Lashyn Kiyekbayeva, Dilek Arslan Ateşşahin, Tamar Goloshvili, Gerardo Leyva-Gómez, Javad Sharifi-Rad
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cancer Cell International
Subjects:
Chemotherapeutic drugs
Indole-3-carbinol (I3C)
3,3'-diindolylmethane (DIM)
Cancer
Anti-tumor action
Online Access:https://doi.org/10.1186/s12935-023-03031-4

Internet

https://doi.org/10.1186/s12935-023-03031-4

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