Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis may reduce risk of subsequent viral challenge.

Immunization by exposure to live virus (SIVmne/HIV-2287) during antiretroviral drug prophylaxis may reduce risk of subsequent viral challenge.

<h4>Rationale/study design</h4>A major challenge in the development of HIV vaccines is finding immunogens that elicit protection against a broad range of viral strains. Immunity to a narrow range of viral strains may protect infants of HIV-infected women or partners discordant for HIV. W...

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Bibliographic Details
Main Authors: Lisa M Frenkel, LaRene Kuller, Ingrid A Beck, Che-Chung Tsai, Jaimy P Joy, Thera M Mulvania, Shiu-Lok Hu, David C Montefiori, David M Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240495

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https://doi.org/10.1371/journal.pone.0240495

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