Energy landscape reveals that the budding yeast cell cycle is a robust and adaptive multi-stage process.

Quantitatively understanding the robustness, adaptivity and efficiency of cell cycle dynamics under the influence of noise is a fundamental but difficult question to answer for most eukaryotic organisms. Using a simplified budding yeast cell cycle model perturbed by intrinsic noise, we systematicall...

Full description

Bibliographic Details
Main Authors: Cheng Lv, Xiaoguang Li, Fangting Li, Tiejun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4368831?pdf=render