Inhibition of gut bacterial β-glucuronidase by chemical components from black tea: Inhibition interactions and molecular mechanism

Inhibition of gut bacterial β-glucuronidase by chemical components from black tea: Inhibition interactions and molecular mechanism

Gut bacterial β-glucuronidase is regarded as an important molecular target for several therapeutic applications. Inhibitors of β-glucuronidase can effectively alleviate the drug-induced gastrointestinal tract toxicity. In this study, the ethanol extracts of black tea was found to display significant...

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Bibliographic Details
Main Authors: Cheng-Peng Sun, Xiang-Ge Tian, Lei Feng, Chao Wang, Jing-Xin Li, Xiao-Kui Huo, Wen-Yu Zhao, Jing Ning, Zhen-Long Yu, Sa Deng, Bao-Jing Zhang, Xia Lv, Jie Hou, Xiao-Chi Ma
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Arabian Journal of Chemistry
Subjects:
β-glucuronidase
Catechins
Theaflavins
Inhibitory kinetics
Molecular simulation
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522100472X

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http://www.sciencedirect.com/science/article/pii/S187853522100472X

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