Accelerated absorption of regular insulin administered via a vascularizing permeable microchamber implanted subcutaneously in diabetic Rattus norvegicus

Accelerated absorption of regular insulin administered via a vascularizing permeable microchamber implanted subcutaneously in diabetic Rattus norvegicus

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In Type 1 diabetes patients, even ultra-rapid acting insulins injected subcutaneously reach peak concentrations in 45 minutes or longer. The lag time between dosing and peak concentration, as well as intra- and inter-subject variability, render prandial glucose control and dose consistency difficult...

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Bibliographic Details
Main Authors: Leah V. Steyn, Delaney Drew, Demetri Vlachos, Barry Huey, Katie Cocchi, Nicholas D. Price, Robert Johnson, Charles W. Putnam, Klearchos K. Papas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310011/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310011/?tool=EBI

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