FBXW7 and Its Downstream NOTCH Pathway Could be Potential Indicators of Organ-Free Metastasis in Colorectal Cancer

FBXW7 and Its Downstream NOTCH Pathway Could be Potential Indicators of Organ-Free Metastasis in Colorectal Cancer

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths globally. Metastasis is associated with a poor prognosis, yet the underlying molecular mechanism(s) remained largely unknown. In this study, a total of 85 CRC patients were included and the primary tumor lesions were evalu...

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Bibliographic Details
Main Authors: Dongzheng Li, Shiye Jiang, Xin Zhou, Chengshuai Si, Peng Shao, Qian Jiang, Liuqing Zhu, Lu Shen, Qi Meng, Jiani C. Yin, Yang Shao, Yueming Sun, Liu Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
organ metastasis
FBXW7
NOTCH
NGS
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.783564/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.783564/full

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