Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells

Hypoxia occurs in human atherosclerotic lesions and has multiple adverse effects on endothelial cell metabolism. Recently, key roles of long non-coding RNAs (lncRNAs) in the development of atherosclerosis have begun to emerge. In this study, we investigate the lncRNA profiles of human umbilical vein...

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Bibliographic Details
Main Authors: Pierre R. Moreau, Tiit Örd, Nicholas L. Downes, Henri Niskanen, Maria Bouvy-Liivrand, Einari Aavik, Seppo Ylä-Herttuala, Minna U. Kaikkonen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
long non-coding RNA
atherosclerosis
hypoxia
endothelial cell
super-enhancer
GRO-Seq
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00159/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2018.00159/full

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