Endothelium-derived Netrin-4 supports pancreatic epithelial cell adhesion and differentiation through integrins α2β1 and α3β1.

Endothelium-derived Netrin-4 supports pancreatic epithelial cell adhesion and differentiation through integrins α2β1 and α3β1.

Netrins have been extensively studied in the developing central nervous system as pathfinding guidance cues, and more recently in non-neural tissues where they mediate cell adhesion, migration and differentiation. Netrin-4, a distant relative of Netrins 1-3, has been proposed to affect cell fate det...

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Bibliographic Details
Main Authors: Mayra Yebra, Giuseppe R Diaferia, Anthony M P Montgomery, Thomas Kaido, William J Brunken, Manuel Koch, Gary Hardiman, Laura Crisa, Vincenzo Cirulli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3146510?pdf=render

Internet

http://europepmc.org/articles/PMC3146510?pdf=render

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