Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process

Overexpression of NT-3 in the hippocampus suppresses the early phase of the adult neurogenic process

The dentate gyrus (DG) of the hippocampus regulates stress-related emotional behaviors and ensures neurogenesis throughout life. Neurotrophin-3 (NT-3) is a neurotrophic factor that regulates neuronal differentiation, survival, and synaptic formation in both the peripheral and central nervous systems...

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Bibliographic Details
Main Authors: Nanami Kasakura, Yuka Murata, Asuka Shindo, Shiho Kitaoka, Tomoyuki Furuyashiki, Kanzo Suzuki, Eri Segi-Nishida
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neuroscience
Subjects:
NT-3
hippocampus
neurogenesis
dentate gyrus
maturation
AAV
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1178555/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1178555/full

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