Bioassay-guided identification of potential Alzheimer’s disease therapeutic agents from Kaempferol-Enriched fraction of Aframomum melegueta seeds using in vitro and chemoinformatics approaches

Bioassay-guided identification of potential Alzheimer’s disease therapeutic agents from Kaempferol-Enriched fraction of Aframomum melegueta seeds using in vitro and chemoinformatics approaches

Alzheimer's disease (AD) has become a major public health concern and the fifth major cause of death among the aging population globally. In this study, the total phenols and flavonoids contents (TPC and TFC) and in vitro antioxidant actions of the methanol extract and the various fractions of...

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Bibliographic Details
Main Authors: Ifeoma Felicia Chukwuma, Timothy Prince Chidike Ezeorba, Florence Nkechi Nworah, Victor Onukwube Apeh, Mohammad Khalid, Sherouk Hussein Sweilam
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Arabian Journal of Chemistry
Subjects:
Aframomum melegueta
Acetylcholinesterase
Antioxidants
Butyrylcholinesterase
Drug-likeness
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223005518

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http://www.sciencedirect.com/science/article/pii/S1878535223005518

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