Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development
The vertebrate-specific proteins astrotactin-1 and 2 (ASTN-1 and ASTN-2) are integral membrane perforin-like proteins known to play critical roles in neurodevelopment, while ASTN-2 has been linked to the planar cell polarity pathway in hair cells. Genetic variations associated with them are linked t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2016-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160053 |