Crocin ameliorates MicroRNAs-associated ER stress in type 2 diabetes induced by methylglyoxal

Objective(s): Methylglyoxal (MG) provokes endoplasmic reticulum (ER) stress in β-cells and triggers pancreatic β-cell dysfunction. Crocin has anti-diabetic properties. The present study investigated whether crocin prevented pancreas damages induced by MG.Materials and Methods: Diabetes was induced b...

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Bibliographic Details
Main Authors: Vahid Radmehr, Akram Ahangarpour, Seyyed Ali Mard, Layasadat Khorsandi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_19607_8ff32b78f0940a44b2d206ce49436d3f.pdf