DG-Affinity: predicting antigen–antibody affinity with language models from sequences

DG-Affinity: predicting antigen–antibody affinity with language models from sequences

Abstract Background Antibody-mediated immune responses play a crucial role in the immune defense of human body. The evolution of bioengineering has led the progress of antibody-derived drugs, showing promising efficacy in cancer and autoimmune disease therapy. A critical step of this development pro...

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Bibliographic Details
Main Authors: Ye Yuan, Qushuo Chen, Jun Mao, Guipeng Li, Xiaoyong Pan
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Bioinformatics
Subjects:
Affinity
Deep learning
Sequence embedding
Antibody–antigen interaction
Online Access:https://doi.org/10.1186/s12859-023-05562-z

Internet

https://doi.org/10.1186/s12859-023-05562-z

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