Extrachromosomal circular DNA in cancer drug resistance and its potential clinical implications

Chemotherapy is widely used to treat patients with cancer. However, resistance to chemotherapeutic drugs remains a major clinical concern. The mechanisms of cancer drug resistance are extremely complex and involve such factors such as genomic instability, DNA repair, and chromothripsis. A recently e...

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Bibliographic Details
Main Authors: Juanjuan Luo, Ying Li, Tangxuan Zhang, Tianhan Xv, Chao Chen, Mengting Li, Qixiang Qiu, Yusheng Song, Shaogui Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1092705/full