Human Placental Syncytiotrophoblasts Restrict <italic toggle="yes">Toxoplasma gondii</italic> Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines

ABSTRACT Toxoplasma gondii is a major source of congenital disease worldwide, but the cellular and molecular factors associated with its vertical transmission are largely unknown. In humans, the placenta forms the key interface between the maternal and fetal compartments and forms the primary barrie...

Full description

Bibliographic Details
Main Authors: Stephanie E. Ander, Elizabeth N. Rudzki, Nitin Arora, Yoel Sadovsky, Carolyn B. Coyne, Jon P. Boyle
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.01678-17