Single-transcript multiplex in situ hybridisation reveals unique patterns of dystrophin isoform expression in the developing mammalian embryo [version 2; peer review: 2 approved]

Background: The dystrophin gene has multiple isoforms: full-length dystrophin (dp427) is principally known for its expression in skeletal and cardiac muscle, but is also expressed in the brain, and several internal promoters give rise to shorter, N-terminally truncated isoforms with wider tissue exp...

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Bibliographic Details
Main Authors: John C. W. Hildyard, Abbe H. Crawford, Faye Rawson, Dominique O. Riddell, Rachel C. M. Harron, Richard J. Piercy
Format: Article
Language:English
Published: Wellcome 2020-07-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/5-76/v2