Synthesis of Some Oxadiazole Derivatives as New Anticandidal Agents
In this study, 5-[(pyrimidin-2-ylthio)methyl]-1,3,4-oxadiazole-2(3H)-thione (3) was synthesized via the ring closure reaction of 2-(pyrimidin-2-ylthio)acetohydrazide (2) with carbon disulphide. New oxadiazole derivatives 4a-f were obtained by the nucleophilic substitution reaction of compound 3 with...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-09-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/16/9/7662/ |