Evaluation of physicochemical properties and in-vitro release profile of glipizide-matrix patch

OBJECTIVES: The aim of the present investigation was to form matrix patches with ethyl cellulose (EC) as the base polymer, polyvinyl pyrrolidone (PVP) as the copolymer, plasticizer with dibutyl phthalate (DBP) or acetyl tributyl citrate (ATBC) and the drug glipizide (gz) by the solvent casting metho...

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Bibliographic Details
Main Authors: Kajal Ghosal, Rajan Rajabalaya, Anindya Kishore Maiti, Bikramaditya Chowdhury, Arunabha Nanda
Format: Article
Language:English
Published: Universidade de São Paulo 2010-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000200007