Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation.

Naked DNA vaccines can be manufactured simply and are stable at ambient temperature, but require improved delivery technologies to boost immunogenicity. Here we explore in vivo electroporation for multivalent codon-optimized human papillomavirus (HPV) L1 and L2 DNA vaccination.Balb/c mice were vacci...

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Bibliographic Details
Main Authors: Kihyuck Kwak, Rosie Jiang, Subhashini Jagu, Joshua W Wang, Chenguang Wang, Neil D Christensen, Richard B S Roden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3607584?pdf=render