<i>Isatis tinctoria</i> L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling
Senescent fibroblasts progressively deteriorate the functional properties of skin tissue. Senescent cells secrete senescence-associated secretory phenotype (SASP) factor, which causes the aging of surrounding non-senescent cells and accelerates aging in the individuals. Recent findings suggested the...
Main Authors: | Jieun Woo, Seoungwoo Shin, Hyanggi Ji, Dehun Ryu, Eunae Cho, Youngseok Kim, Junoh Kim, Deokhoon Park, Eunsun Jung |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
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Series: | Nutrients |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6643/14/9/1979 |
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