Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens

Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens

ABSTRACT Avian pathogenic Escherichia coli (APEC) associated with colibacillosis results in high morbidity and mortality, and severe economic losses to the poultry industry. APEC is a zoonotic pathogen and can infect humans through contaminated poultry products. Vaccination and antibiotic treatment...

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Bibliographic Details
Main Authors: Yosra A. Helmy, Dipak Kathayat, Loic Deblais, Vishal Srivastava, Gary Closs, Robert J. Tokarski, Oluwatosin Ayinde, James R. Fuchs, Gireesh Rajashekara
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
APEC
quorum sensing
inhibitors
anti-virulence
auto-inducer 2
QSI-5
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00286-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00286-22

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