Effect of rofecoxib on colon chemical carcinogenesis at colonic anastomotic area in the rat Influencia del rofecoxib en la carcinogénesis cólica perianastomótica inducida en ratas

Aim: to investigate the effect of the selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib on the incidence of perianastomotic colonic tumors in a model of chemical carcinogenesis in the rat. Experimental design: experimental study with 45 male Sprague-Dawley rats randomly assigned to one of three...

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Bibliographic Details
Main Authors: J. F. Noguera Aguilar, I. Amengual Antich, J. M. Morón Canis, A. Plaza Martínez, J. A. Martínez Córcoles, C. Tortajada Collado, J. J. Pujol Tugores
Format: Article
Language:English
Published: Aran Ediciones 2005-06-01
Series:Revista Espanola de Enfermedades Digestivas
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Online Access:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082005000600003