Keap1 governs ageing-induced protein aggregation in endothelial cells

The breach of proteostasis, leading to the accumulation of protein aggregates, is a hallmark of ageing and age-associated disorders, up to now well-established in neurodegeneration. Few studies have addressed the issue of dysfunctional cell response to protein deposition also for the cardiovascular...

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Bibliographic Details
Main Authors: Aleksandra Kopacz, Damian Kloska, Marta Targosz-Korecka, Bartłomiej Zapotoczny, Dominik Cysewski, Nicolas Personnic, Ewa Werner, Karolina Hajduk, Alicja Jozkowicz, Anna Grochot-Przeczek
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172030166X