Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome.

Escherichia coli is an important cause of bloodstream infections (BSI), which is of concern given its high mortality and increasing worldwide prevalence. Finding bacterial genetic variants that might contribute to patient death is of interest to better understand infection progression and implement...

Full description

Bibliographic Details
Main Authors: Erick Denamur, Bénédicte Condamine, Marina Esposito-Farèse, Guilhem Royer, Olivier Clermont, Cédric Laouenan, Agnès Lefort, Victoire de Lastours, Marco Galardini, COLIBAFI, SEPTICOLI groups
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010112