Sevoflurane Exposure in the Developing Brain Induces Hyperactivity, Anxiety–Free, and Enhancement of Memory Consolidation in Mice

Sevoflurane Exposure in the Developing Brain Induces Hyperactivity, Anxiety–Free, and Enhancement of Memory Consolidation in Mice

BackgroundSevoflurane exposure at brain developmental stages has been reported to induce neurotoxicity and, subsequently, results in learning deficits at the juvenile age. In this study, we aimed to investigate the effects of prior early-age sevoflurane exposure on locomotor activity, anxiety, CA1-d...

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Bibliographic Details
Main Authors: Rui Li, Bei Wang, Xiaohong Cao, Chao Li, Yuhan Hu, Dandan Yan, Yanchang Yang, Liqing Wang, Lingzhong Meng, Zhiyong Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
pediatric anesthesia
neurotoxicity
sevoflurane
hippocampus
cognition
synapse plasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.934230/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.934230/full

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