A variant of Runx2 that differs from the bone isoform in its splicing is expressed in spermatogenic cells

Background. Members of the Runx gene family encode transcription factors that bind to DNA in a sequence-specific manner. Among the three Runx proteins, Runx2 comprises 607 amino acid (aa) residues, is expressed in bone, and plays crucial roles in osteoblast differentiation and bone development. We e...

Full description

Bibliographic Details
Main Authors: Satoru Kanto, Marcin Grynberg, Yoshiyuki Kaneko, Jun Fujita, Masanobu Satake
Format: Article
Language:English
Published: PeerJ Inc. 2016-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/1862.pdf