Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons

<p>Abstract</p> <p>Background</p> <p>We have previously demonstrated that PDGF receptor activation indirectly inhibits N-methyl-D-aspartate (NMDA) currents by modifying the cytoskeleton. PDGF receptor ligand is also neuroprotective in hippocampal slices and cultured neu...

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Bibliographic Details
Main Authors: Beazely Michael A, Weerapura Manjula, MacDonald John F
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/1/1/20