Pregabalin attenuates long-lasting post-inflammatory nociplastic mechanical sensitization in mice

Nociplastic pain, the most recently proposed mechanistic descriptor of chronic pain, is the pain resulting from an altered nociceptive system and network without clear evidence of nociceptor activation, injury or disease in the somatosensory system. As the pain-associated symptoms in many patients s...

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Bibliographic Details
Main Authors: Manami Yajima, Yukari Takahashi, Yae K. Sugimura, Fusao Kato
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Neurobiology of Pain
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452073X23000181