Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

Abstract Background Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic modification that is detectable in peripheral patient fluids such as urine and blood plasma that could serve as a non-invasive diagn...

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Bibliographic Details
Main Authors: Marie K. Kirby, Ryne C. Ramaker, Brian S. Roberts, Brittany N. Lasseigne, David S. Gunther, Todd C. Burwell, Nicholas S. Davis, Zulfiqar G. Gulzar, Devin M. Absher, Sara J. Cooper, James D. Brooks, Richard M. Myers
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Cancer
Subjects:
DNA methylation
Prostate cancer
EZH2
Biomarker
Diagnostic
Online Access:http://link.springer.com/article/10.1186/s12885-017-3252-2

Internet

http://link.springer.com/article/10.1186/s12885-017-3252-2

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