Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets

Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets

Abstract CRISPR-Cas systems have been widely used in genome editing and transcriptional regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its adjustable properties, such as simplicity of design, easy operation, collateral cleavage activity, and high biocompatib...

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Bibliographic Details
Main Authors: Ulhas Sopanrao Kadam, Yuhan Cho, Tae Yoon Park, Jong Chan Hong
Format: Article
Language:English
Published: SpringerOpen 2023-02-01
Series:Applied Biological Chemistry
Subjects:
Biomarker
Pathogen
Disease diagnostics
CRISPR-Cas
Cas12a
Cas13a
Online Access:https://doi.org/10.1186/s13765-023-00771-9

Internet

https://doi.org/10.1186/s13765-023-00771-9

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