The Effects of rs405509 on APOEε4 Non-carriers in Non-demented Aging

The Effects of rs405509 on APOEε4 Non-carriers in Non-demented Aging

BackgroundThere is evidence that the T allele of rs405509 located in the apolipoprotein E (APOE) promotor region is a risk factor for Alzheimer’s disease (AD). However, the effect of the T/T allele on brain function in non-demented aging is still unclear.MethodsWe analyzed the effects of the rs40550...

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Bibliographic Details
Main Authors: Dongpeng Wu, Han Zhao, Huali Gu, Bin Han, Qingqing Wang, Xu Man, Renliang Zhao, Xuejun Liu, Jinping Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Neuroscience
Subjects:
APOEε4
Alzheheimer’s disease
rs405509
amplitude of low-frequency fluctuations
degree centrality (DC)
regional homogeneity (ReHo)
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.677823/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.677823/full

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