Advances in the Structure of GGGGCC Repeat RNA Sequence and Its Interaction with Small Molecules and Protein Partners

Advances in the Structure of GGGGCC Repeat RNA Sequence and Its Interaction with Small Molecules and Protein Partners

The aberrant expansion of GGGGCC hexanucleotide repeats within the first intron of the <i>C9orf72</i> gene represent the predominant genetic etiology underlying amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). The transcribed r(GGGGCC)<sub>n</sub> RNA...

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Bibliographic Details
Main Authors: Xiaole Liu, Xinyue Zhao, Jinhan He, Sishi Wang, Xinfei Shen, Qingfeng Liu, Shenlin Wang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Molecules
Subjects:
amyotrophic lateral sclerosis
frontotemporal dementia
<i>C9orf72</i>
GGGGCC
G4
Online Access:https://www.mdpi.com/1420-3049/28/15/5801

Internet

https://www.mdpi.com/1420-3049/28/15/5801

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