A dual dynamically cross-linked hydrogel promotes rheumatoid arthritis repair through ROS initiative regulation and microenvironment modulation-independent triptolide release

A dual dynamically cross-linked hydrogel promotes rheumatoid arthritis repair through ROS initiative regulation and microenvironment modulation-independent triptolide release

High oxidative stress and inflammatory cell infiltration are major causes of the persistent bone erosion and difficult tissue regeneration in rheumatoid arthritis (RA). Triptolide (TPL) has become a highly anticipated anti-rheumatic drug due to its excellent immunomodulatory and anti-inflammatory ef...

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Bibliographic Details
Main Authors: Tianyang Wang, Cheng Huang, Ziyuan Fang, Abudureheman Bahatibieke, Danping Fan, Xing Wang, Hongyan Zhao, Yajie Xie, Kun Qiao, Cheng Xiao, Yudong Zheng
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Triptolide
ROS responsiveness
Macrophage polarization
Rheumatoid arthritis
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424001017

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http://www.sciencedirect.com/science/article/pii/S2590006424001017

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