NanoUPLC-QTOF-MS/MS Determination of Major Rosuvastatin Degradation Products Generated by Gamma Radiation in Aqueous Solution

NanoUPLC-QTOF-MS/MS Determination of Major Rosuvastatin Degradation Products Generated by Gamma Radiation in Aqueous Solution

Rosuvastatin, a member of the statin family of drugs, is used to regulate high cholesterol levels in the human body. Moreover, rosuvastatin and other statins demonstrate a protective role against free radical-induced oxidative stress. Our research aimed to investigate the end-products of free radica...

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Bibliographic Details
Main Authors: Lucija Dončević, Ema Svetličić, Amela Hozić, Branka Mihaljević, Dorota Jarmużek, Ivana Tartaro Bujak, Donata Pluskota-Karwatka, Luka Ozdanovac, Iva Džeba, Mario Cindrić
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceuticals
Subjects:
rosuvastatin
nanoLC-MS
gamma radiation
degradation products identification
OH radical mechanisms
Online Access:https://www.mdpi.com/1424-8247/14/11/1160

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https://www.mdpi.com/1424-8247/14/11/1160

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