MUTAGENIC ACTIVITY OF TILORONE – ACTIVE PHARMACEUTICAL SUBSTANCE OF AMIXIN IN MICROTITER PLATE VARIANT OF AMES TEST

Aim – to discover potential mutagenic activity of tilorone – active pharmaceutical substance of amixin. Methods. Mutagenic activity of tilorone was studied in the Ames test on Salmonella typhimurium ТА 98 (frame-shift mutations) and ТА 100 (Dot mutations – base pars change). Tilorone was examined in...

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Bibliographic Details
Main Authors: Т. О. Філіпова, М. Б. Галкін, М. Я. Головенко
Format: Article
Language:English
Published: Odessa I. I. Mechnikov National University 2018-03-01
Series:Mìkrobìologìâ ì Bìotehnologìâ
Subjects:
Online Access:http://mbt.onu.edu.ua/article/view/126657