MUTAGENIC ACTIVITY OF TILORONE – ACTIVE PHARMACEUTICAL SUBSTANCE OF AMIXIN IN MICROTITER PLATE VARIANT OF AMES TEST
Aim – to discover potential mutagenic activity of tilorone – active pharmaceutical substance of amixin. Methods. Mutagenic activity of tilorone was studied in the Ames test on Salmonella typhimurium ТА 98 (frame-shift mutations) and ТА 100 (Dot mutations – base pars change). Tilorone was examined in...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Odessa I. I. Mechnikov National University
2018-03-01
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Series: | Mìkrobìologìâ ì Bìotehnologìâ |
Subjects: | |
Online Access: | http://mbt.onu.edu.ua/article/view/126657 |