Hydrophobic Amino Acids as Universal Elements of Protein-Induced DNA Structure Deformation

Interaction with the DNA minor groove is a significant contributor to specific sequence recognition in selected families of DNA-binding proteins. Based on a statistical analysis of 3D structures of protein–DNA complexes, we propose that distortion of the DNA minor groove resulting from interactions...

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Bibliographic Details
Main Authors: Kateřina Faltejsková, David Jakubec, Jiří Vondrášek
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/11/3986