The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway

The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway

Abstract Background Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydrolase enzymes that lacks the amino acid residues necessary for catalyti...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Lei Tian, Tianwei Guo, Fujian Wu, Rui Bai, Sinan Ai, Hongyue Wang, Yuanxiu Song, Min Zhu, Youxu Jiang, Shuhong Ma, Xiaofeng Zhuang, Shuzhen Guo
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: BMC 2023-10-01
Sraith:Stem Cell Research & Therapy
Ábhair:
ADPRHL1
CRISPR/cas9
ROCK pathway
Focal adhesions
Rochtain ar líne:https://doi.org/10.1186/s13287-023-03507-0

Ar líne

https://doi.org/10.1186/s13287-023-03507-0

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